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| Ulcerated Colitis |
| Ulcerated Colitis or Ulcerative colitis (UC) is the inflammation of the inner lining of intestine (colon) and the rectum. Both become red, swollen, and ulcerated. Drug treatment is effective for about 70-80% of patients; Ileostomysurgery becomes necessary in the remaining 20-30%.
The procedure results in removing colon & rectum, with options of BCIR type Kock pouch continent ileostomy or conventional ileostomy or by leaving the anal sphincter muscle intact. J-pouch or reservoir is surgically constructed from the small intestine. An opening is made at the bottom of the pouch & sewn or stapled to the anal muscles to restore the intestinal passage.
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(source: Southern Medical Journal).
More Information (source: Southern Medical Journal).
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12/31/1969 03:59 PM
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Ischemic Colitis: A Clinical Review
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Ischemic colitis is the most common form of intestinal ischemia. It manifests as a spectrum of injury from transient self-limited ischemia involving the mucosa and submucosa to acute fulminant ischemia with transmural infarction that may progress to necrosis and death. Although there are a variety of causes, the most common mechanism is an acute, self-limited compromise in intestinal blood flow. Patients typically have mild abdominal pain and tenderness over the involved segment of bowel. There is usually passage of blood mixed with stool, but hemodynamically significant bleeding is unusual. Although computed tomography may have suggestive findings, colonoscopy is the procedure of choice for diagnosis. Supportive care with intravenous fluids, optimization of hemodynamic status, avoidance of vasoconstrictive drugs, bowel rest, and empiric antibiotics will produce clinical improvement within 1 to 2 days in most patients. Twenty percent of patients will have development of peritonitis or may deteriorate despite conservative management and will require surgery.
(C) 2005 Southern Medical Association
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12/31/1969 03:59 PM
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Fibrosing Colonopathy in an Adult Cystic Fibrosis Patient After Discontinuing Pancreatic Enzyme Therapy
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Fibrosing colonopathy, a complication of cystic fibrosis, has generally been reported in young children with exposure to high doses of pancreatic enzymes. The authors report the case of a 25-year-old male with cystic fibrosis who presented with gradually progressive symptoms of bowel obstruction. Pathologic examination of the right colon revealed findings consistent with fibrosing colonopathy. This case is distinctive because of the adult presentation, and because the patient's symptoms developed long after he had discontinued taking a high-strength enzyme preparation. This case suggests that multiple etiologic factors, and not simply exposure to pancreatic enzymes, may result in fibrosing colonopathy in adults with cystic fibrosis.
(C) 2004 Southern Medical Association
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